For Low Risk CSPs, what is the beyond-use date (BUD) at room temperature?

For low-risk compounded sterile preparations (CSPs), the beyond-use date (BUD) at room temperature is established as 48 hours. This timeframe is based on the need to minimize the risk of microbial contamination and ensure the stability of the preparation when stored outside of refrigeration or controlled temperature environments.

The 48-hour guideline allows sufficient time for administration while also upholding patient safety by addressing the increased risk of microbial growth in the absence of refrigeration. This is important to remember when preparing low-risk CSPs, as adhering to the correct BUD is crucial to maintain efficacy and safety for patients receiving these sterile products.

Understanding these guidelines helps pharmacists manage and optimize their compounding practices, ensuring they provide safe, effective care in a clinical setting.