What is the primary purpose of a CACI (Compounding Aseptic Containment Isolator)?

The primary purpose of a Compounding Aseptic Containment Isolator (CACI) is to offer personnel protection during the preparation of cytotoxic drugs. CACI systems are designed to safely handle hazardous materials while ensuring that the compounds remain sterile and free from contamination. This is particularly crucial when working with cytotoxic agents, which can pose significant health risks to pharmacy staff if inhaled or absorbed through the skin.

CACIs achieve this by creating a controlled environment that isolates the hazardous substances from both the operator and the environment. They utilize High Efficiency Particulate Air (HEPA) filtration systems and negative pressure to prevent the escape of potentially harmful aerosols, thereby protecting the health of the personnel involved in compounding. While these isolators can also aid in maintaining sterility, their paramount role is to ensure that the individuals preparing the compounds are not exposed to the risks associated with these dangerous drugs.