What protective equipment is necessary for personnel working with cytotoxic drugs?

Personnel working with cytotoxic drugs must use appropriate protective equipment to minimize the risk of exposure to hazardous materials. The correct answer includes gloves, masks, and gowns with tight cuffs, as these items collectively form a comprehensive barrier against potential contaminants.

Gloves are essential to protect the skin from direct contact with cytotoxic agents, which can be harmful if absorbed through the skin. Masks are necessary to prevent inhalation of airborne particles and vapors that may occur during the handling of these substances, thereby safeguarding respiratory health. Gowns with tight cuffs add an additional layer of protection by preventing any seepage or splashes from contacting the skin and clothing. This is especially important given the potent nature of cytotoxic drugs, which can pose serious health risks.

In contrast to this correct answer, options that describe lesser forms of protection, such as only gloves and masks or standard lab coats, do not fully address the need to provide a complete barrier to prevent exposure. Regular clothing is insufficient as it does not provide the necessary protection against the unique risks that cytotoxic drugs present. Ensuring that the right combination of protective equipment is used is critical in environments where these drugs are handled, as it helps maintain safety and compliance with health regulations.