Which of the following drugs is included in Schedule 5?

Promethazine with codeine is classified as a Schedule V controlled substance due to its specific formulation and use. Schedule V drugs consist of substances that have a lower potential for abuse relative to those in Schedules I-IV but can still lead to mild physical or psychological dependence.

Promethazine is an antipsychotic, and when combined with codeine — an opioid — it creates a medication often used for cough suppression. The presence of codeine, even in a lower strength variation, is what places the combination in Schedule V. This classification reflects regulatory intentions to minimize the risk of misuse while permitting legitimate medical use for managing specific conditions like cough due to cold or flu.

In contrast, the other medications listed have higher abuse potential or are categorized differently based on their pharmacological effects and risk factors. Understanding the scheduling of controlled substances is crucial for ensuring safe prescribing practices and compliance with federal and state regulations.