Which reference is necessary in an institutional pharmacy for IV admixture compatibility?

The reference that is essential in an institutional pharmacy for IV admixture compatibility is Trissel's Guide to IV Compatibility. This guide is specifically designed to provide detailed information on the compatibility and stability of various intravenous medications, which is critical for preventing adverse reactions when multiple medications are mixed or administered concurrently.

In an institutional setting, where there is a high demand for IV medications, ensuring that the drugs are compatible is vital to patient safety. The guide includes empirical data, clinical studies, and consensus recommendations, making it a trusted resource for pharmacists and healthcare professionals involved in the preparation and administration of IV therapies.

While other references may provide useful information in areas of drug interactions, pharmacology, or general medication safety, Trissel's Guide is uniquely focused on intravenous compatibility issues, which is why it is the most appropriate choice in this context.